Study of immunohistochemical demonstration of Bcl-2 protein in ameloblastoma and keratocystic odontogenic tumor
نویسندگان
چکیده
منابع مشابه
Comparative immunohistochemical study of Bcl-X in ameloblastoma, keratocystic odontogenic tumor and adenomatoid odontogenic tumor
OBJECTIVES Since its recognition as a physiologic process associated with tumor, among molecular mechanisms involved in tumor progression, defects in regulation of apoptosis have generated an accelerating volume of research that has sought to elucidate the role of programed cell death in pathogenesis and treatment of various tumors. Therefore, this study was performed to understand better the d...
متن کاملimmunohistochemical analysis of cox-2 expression in dentigerous cyst, keratocystic odontogenic tumor and ameloblastoma: a comparative study
background: cyclo-oxygenase-2 (cox-2) is an early response gene that is induced by growth factors, oncogenes and carcinogens and its expression is increased in various tumors. increased expression of cox-2 plays a signifi cant role in the development and growth of tumors by interfering in biological processes such as cell division, cellular immunity, cell adhesion, apoptosis, and angiogenesis. ...
متن کاملBioinformatics Analysis Reveals Genes Involved in the Pathogenesis of Ameloblastoma and Keratocystic Odontogenic Tumor
Pathogenesis of odontogenic tumors is not well known. It is important to identify genetic deregulations and molecular alterations. This study aimed to investigate, through bioinformatic analysis, the possible genes involved in the pathogenesis of ameloblastoma (AM) and keratocystic odontogenic tumor (KCOT). Genes involved in the pathogenesis of AM and KCOT were identified in GeneCards. Gene lis...
متن کاملa comparative immunohistochemical study of ki-67 and bcl-2 expression in solid ameloblastoma and adenomatoid odontogenic tumor
background: solid ameloblastoma (sab) is an invasive tumor which infiltrates adjacent normal tissues. adenomatoid odontogenic tumor is a noninvasive tumor and never infiltrates surrounding normal tissues. the purpose of this study was to determine the biological behavior of these two epithelial odontogenic neoplasm by detecting ki-67 and bcl-2, which are mitotic and anti apoptotic markers respe...
متن کاملcomparison of immunohistochemical expression of cd10 in keratocystic odontogenic tumor and ameloblastoma
background: odontogenic keratocyst (okc), also called keratocystic odontogenic tumor (kcot), is a developmental lesion which should be carefully monitored and it exhibits development mechanisms and biologic behaviors different from those of other more common lesions such as dentigerous and radicular cysts. cd10 antigen is a cell surface metalloendopeptidase, which inactivates various peptides t...
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ژورنال
عنوان ژورنال: Journal of Oral and Maxillofacial Pathology
سال: 2013
ISSN: 0973-029X
DOI: 10.4103/0973-029x.119750